Recombinant DNA (rDNA) refers to artificial DNA molecules that are created by combining genetic material from different sources. This technology involves the insertion of DNA fragments from one ...

In the summer of 1974, a group of international researchers published an urgent open letter asking their colleagues to suspend work on a potentially dangerous new technology. The letter was a first in ...

One of the greatest transformations in modern medicine arguably began with a corned beef sandwich. It was the late 1960s, and new Department of Medicine Chair Lloyd Hollingsworth “Holly” Smith Jr., MD ...

The first peer-reviewed journal in the field of human gene therapy, providing all-inclusive coverage of the research, methods, and clinical developments that are driving today's explosion of gene ...

A new study in the journal Human Gene Therapy indicates that DNA impurities derived from plasmid and host cell DNA are encapsulated into recombinant adeno-associated virus (rAAV) capsids as ...